Saturday's game between the St. Louis Cardinals (23-30) and Cleveland Guardians (22-28) squaring off at Progressive Field has a projected final score of 5-3 (based on our computer prediction) in favor of the Cardinals, so it should be a tight matchup. The game will start at 7:15 PM ET on May 27.

The Guardians will look to Tanner Bibee (1-1) versus the Cardinals and Jack Flaherty (3-4).

Guardians vs. Cardinals Game Info & Odds

  • When: Saturday, May 27, 2023 at 7:15 PM ET
  • Where: Progressive Field in Cleveland, Ohio
  • How to Watch on TV: FOX
  • Live Stream: Watch this game on Fubo!

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Guardians vs. Cardinals Score Prediction

Our pick for this game is Cardinals 5, Guardians 4.

Total Prediction for Guardians vs. Cardinals

  • Total Prediction: Over 8 runs

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Discover More About This Game

Guardians Performance Insights

  • The Guardians have played as the favorite in five of their past 10 games and won two of those contests.
  • When it comes to hitting the over, Cleveland and its opponents are 3-6-1 in its last 10 games with a total.
  • The Guardians have a record of 1-1-0 ATS over their last 10 games.
  • The Guardians have been favorites in 29 games this season and won 14 (48.3%) of those contests.
  • Cleveland is 14-16 this season when entering a game favored by -110 or more on the moneyline.
  • Oddsmakers have implied with the moneyline set for this matchup that the Guardians have a 52.4% chance to win.
  • Cleveland has scored the fewest runs in the majors this season with just 173 (3.5 per game).
  • The Guardians' 3.86 team ERA ranks ninth across all league pitching staffs.

Cardinals Performance Insights

  • The Cardinals have played as the underdog in four of their past 10 games and have gone 2-2 in those contests.
  • In its last 10 games with an over/under, St. Louis and its opponents have combined to eclipse the total six times.
  • The Cardinals have had a spread set in one of their past 10 games, and they have failed to cover the spread each time.
  • The Cardinals have been underdogs in 21 games this season and have come away with the win nine times (42.9%) in those contests.
  • St. Louis has a win-loss record of 9-12 when favored by -110 or worse by sportsbooks this year.
  • The Cardinals have an implied victory probability of 52.4% according to the moneyline set by oddsmakers for this matchup.
  • St. Louis is the fifth-highest scoring team in baseball, averaging five runs per game (266 total).
  • The Cardinals have pitched to a 4.34 ERA this season, which ranks 17th in baseball.

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Guardians Schedule

Date Opponent Score Pitching Matchup
May 21 @ Mets L 2-1 Shane Bieber vs Justin Verlander
May 22 White Sox W 3-0 Hunter Gaddis vs Jimmy Lambert
May 23 White Sox L 4-2 Logan Allen vs Dylan Cease
May 24 White Sox L 6-0 Cal Quantrill vs Michael Kopech
May 26 Cardinals W 4-3 Shane Bieber vs Matthew Liberatore
May 27 Cardinals - Tanner Bibee vs Jack Flaherty
May 28 Cardinals - Hunter Gaddis vs Jordan Montgomery
May 29 @ Orioles - Logan Allen vs Tyler Wells
May 30 @ Orioles - Cal Quantrill vs Kyle Gibson
May 31 @ Orioles - Shane Bieber vs Grayson Rodriguez
June 1 @ Twins - Tanner Bibee vs Pablo Lopez

Cardinals Schedule

Date Opponent Score Pitching Matchup
May 22 @ Reds L 6-5 Jordan Montgomery vs Brandon Williamson
May 23 @ Reds W 8-5 Adam Wainwright vs Graham Ashcraft
May 24 @ Reds L 10-3 Steven Matz vs Ben Lively
May 25 @ Reds W 2-1 Miles Mikolas vs Luke Weaver
May 26 @ Guardians L 4-3 Matthew Liberatore vs Shane Bieber
May 27 @ Guardians - Jack Flaherty vs Tanner Bibee
May 28 @ Guardians - Jordan Montgomery vs Hunter Gaddis
May 29 Royals - Adam Wainwright vs TBA
May 30 Royals - Miles Mikolas vs Zack Greinke
June 2 @ Pirates - Miles Mikolas vs Roansy Contreras
June 3 @ Pirates - Matthew Liberatore vs TBA